OCRA

Below you will find links to all our next-gen sequencing data by type. The same information is available broken down by themes on themes pages and publication pages.

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What is next gen sequencing? This technology involves breaking the genome up into tiny fragments and then determining the sequence of individual base pairs (A, C, G, T) using another technique called PCR. Each sequence produces a “read” which is then aligned to the known sequence of the genome to match its location of origin. Prior to sequencing, the fragments are selectively enriched by association to other proteins of interest such as transcription factors. We can also detect methylation of individual reads, which is a key signal of cellular aging and provides clues to the origin of cancer.